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Rapidly detecting disorder in rhythmic biological signals: A spectral entropy measure to identify cardiac arrhythmias

机译:快速检测节律性生物信号的紊乱:光谱   熵测量识别心律失常

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摘要

We consider the use of a running measure of power spectrum disorder todistinguish between the normal sinus rhythm of the heart and two forms ofcardiac arrhythmia: atrial fibrillation and atrial flutter. This spectralentropy measure is motivated by characteristic differences in the spectra ofbeat timings during the three rhythms. We plot patient data derived fromten-beat windows on a "disorder map" and identify rhythm-defining ranges in thelevel and variance of spectral entropy values. Employing the spectral entropywithin an automatic arrhythmia detection algorithm enables the classificationof periods of atrial fibrillation from the time series of patients' beats. Whenthe algorithm is set to identify abnormal rhythms within 6 s it agrees with85.7% of the annotations of professional rhythm assessors; for a response timeof 30 s this becomes 89.5%, and with 60 s it is 90.3%. The algorithm provides arapid way to detect atrial fibrillation, demonstrating usable response times aslow as 6 s. Measures of disorder in the frequency domain have practicalsignificance in a range of biological signals: the techniques described in thispaper have potential application for the rapid identification of disorder inother rhythmic signals.
机译:我们考虑使用功率谱障碍的连续测量来区分心脏的正常窦性心律和两种形式的心律失常:房颤和房扑。这种频谱熵测度是由三个节奏中拍子时序频谱中的特征差异引起的。我们将来自拍子窗口的患者数据绘制在“失调图”上,并在频谱熵值的水平和方差中确定节奏定义范围。在自动心律失常检测算法中使用频谱熵可以根据患者心跳的时间序列对心房颤动的周期进行分类。当算法设置为在6 s内识别异常节律时,它与专业节律评估者注释的85.7%一致;对于30 s的响应时间,该值为89.5%,而对于60 s的响应时间为90.3%。该算法提供了一种快速的方法来检测心房颤动,表明可用的响应时间低至6 s。频域中无序的测量在一系列生物信号中具有实际意义:本文描述的技术在快速识别其他有节奏信号中的无序中具有潜在的应用。

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